AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

We are currently hiring a highly motivated Associate Scientist II to join our tLNP drug product formulation and process development team. In this role, you will directly work on formulation and process development of the most exciting tLNP drug product, to support emerging research pipelines.

This position will report into the Principal Scientist and based at our San Diego office. This role will involve hands-on laboratory work. All duties will be performed in compliance with AbbVies standard operating procedures (SOPs).

Experience with lipid nanoparticle formulation and purification processes, or experience with process development, engineering and manufacturing of biologics drug product processes are highly desired.

Responsibilities & Duties:

• Prepare, formulate, and characterize nucleic based complex lipid nanoparticle formulations.
• Design, execute, and analyze DOE-based formulation experiments to develop and optimize novel LNP formulations and novel process development.
• Develop novel formulation and conjugation process for lipid nanoparticles based nucleic acid formulations with targeting modalities as well as scale up process.
• Perform investigations of aberrant results, determination of root causes, and recommend action plan to ensure process robustness.
• Maintain proper documentation of all experimental procedures and results, including batch records, protocols, Standard Operating Procedures (SOPs) and other manufacturing related documentation.
• Prepare technical reports and presentations which summarize procedures, study results, and data interpretation as needed.
• Work with other formulations and/or colleagues in other departments as a team, deliver high quality results in an accurate and time sensitive manner.

• Bachelors Degree, or equivalent education, with3 or more years experience or Masters Degree or equivalent education (no additional experience).
• Understanding of lipid-based delivery systems and formulation science principles.
• Hands-on experience working with nucleic acid and/or lipid nanoparticle-based formulations, complex/nanoparticle formulations, other biological formulation, and working knowledge of tangential flow filtration or other purification processes.
• Ability to work in a well-lit heated and/or air-conditioned indoor office and occasional laboratory setting with adequate ventilation. Light physical activity performing non-strenuous daily activities of a productive/technical nature. May require long periods of standing/sitting.
• Comfortable working in a highly innovative, changing, fast-paced environment with multi-task skills is required.
• Ability to work under pressure and tight deadlines. Has the discipline to stay focused and complete specific tasks
• Detail oriented with good organizational skills. A team player with excellent verbal and written communication skills.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location,andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

• This job is eligible to participate in our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's soleandabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Company Name: AbbVie
Website: https://careers.abbvie.com/en/job/a...
Company Description:

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